CBD and Mood: Can Cannabidiol Really Make You Angry?

Can Cannabidiol Really Make You Angry?

Cannabidiol (CBD) is a natural compound found in the cannabis plant that has become increasingly popular due to its potential health benefits. It is often used to help with anxiety, depression, pain, and sleep issues. While there are many potential benefits of using CBD, some people have reported experiencing anger or irritability as a side effect.

However, it is important to note that research on the effects of CBD on mood is still in its early stages, and the evidence is mixed. Some studies have suggested that CBD can help reduce symptoms of anxiety and depression, which are often associated with feelings of anger or irritability. Other studies have suggested that CBD may actually increase feelings of aggression in some individuals.

One possible explanation for the conflicting evidence is that the effects of CBD on mood may depend on a variety of factors, including the individual’s age, gender, and overall health status, as well as the dose and method of administration. Additionally, CBD can interact with other medications, which may also influence its effects on mood.

It is also worth noting that anger or irritability may not necessarily be caused directly by CBD, but may instead be the result of other factors such as stress, sleep deprivation, or other underlying health issues. It is always important to talk to a healthcare professional before starting any new supplement or medication, especially if you have a history of mental health issues or are taking other medications.

Overall, while some people may experience anger or irritability as a side effect of using CBD, the evidence on this topic is still limited and conflicting. More research is needed to fully understand the potential effects of CBD on mood, and to identify any potential risks or benefits associated with its use. If you are considering using CBD for any reason, it is always a good idea to speak with a healthcare professional to determine whether it is a safe and appropriate option for you.


1. What Is CBD And How Does It Work?

2. The Potential Health Benefits Of Using CBD

3. Reported Side Effects Of CBD Use

4. Studies On The Effects Of CBD On Mood

5. The Relationship Between CBD And Anxiety

6. The Relationship Between CBD And Depression

7. The Relationship Between CBD And Anger

8. Factors That May Influence The Effects Of CBD On Mood

9. CBD Interactions With Other Medications

10. Other Potential Causes Of Anger Or Irritability

11. Safety Concerns Associated With CBD Use

12. Dosage And Administration Of CBD

13. Recommendations For Using CBD Safely And Effectively

14. Future Research On CBD And Its Potential Effects On Mood

What Is Cbd And How Does It Work?

Cannabidiol, or CBD, is a natural compound found in the cannabis plant. Unlike tetrahydrocannabinol (THC), another compound found in cannabis, CBD does not produce the same psychoactive effects or “high.” Instead, CBD is believed to have a range of potential health benefits due to its interaction with the body’s endocannabinoid system (ECS).

The ECS is a complex network of receptors and enzymes that helps regulate a variety of bodily functions, including mood, appetite, sleep, and immune response. CBD is thought to interact with these receptors, particularly the CB1 and CB2 receptors, to help regulate these functions and promote balance within the body.

One way that CBD may work is by increasing levels of anandamide, a neurotransmitter that is sometimes called the “bliss molecule” due to its ability to promote feelings of happiness and well-being. CBD may also inhibit the breakdown of anandamide, allowing it to remain in the body for longer periods of time.

Overall, while more research is needed to fully understand the mechanisms by which CBD works, it is believed to interact with the body’s endocannabinoid system to promote balance and regulate various bodily functions.

The Potential Health Benefits Of Using CBD

CBD has been widely studied for its potential health benefits, and researchers have found that it may have a wide range of therapeutic uses. Some of the potential health benefits of using CBD include:

  • Anxiety relief: CBD may help reduce symptoms of anxiety by interacting with the body’s endocannabinoid system and promoting feelings of calm and relaxation.
  • Pain relief: CBD may help reduce pain and inflammation by interacting with the body’s pain receptors and reducing the production of inflammatory molecules.
  • Sleep improvement: CBD may help improve sleep quality by reducing symptoms of anxiety and promoting relaxation.
  • Neuroprotective effects: CBD may have neuroprotective effects, which means it may help protect the brain from damage and promote healthy brain function.
  • Anti-seizure effects: CBD has been approved by the FDA as a treatment for certain types of epilepsy, and research suggests that it may have anti-seizure effects.
  • Cancer treatment: While more research is needed, some studies have suggested that CBD may have anti-tumor effects and may help improve the effectiveness of certain cancer treatments.
  • Acne reduction: CBD may help reduce acne by reducing inflammation and regulating the production of sebum, an oily substance that can contribute to acne.

Overall, while more research is needed to fully understand the potential health benefits of using CBD, early studies have shown promising results in a variety of areas. It is important to note that CBD should not be used as a substitute for medical treatment, and anyone considering using CBD for health reasons should speak with a healthcare professional first.

Reported Side Effects Of CBD Use

While CBD is generally considered safe, there are some reported side effects associated with its use. These side effects are typically mild, and may include:

  • Dry mouth: CBD may cause dry mouth, also known as cottonmouth, due to its ability to reduce saliva production.
  • Changes in appetite: Some users have reported changes in appetite, either an increase or decrease in hunger, after using CBD.
  • Fatigue: CBD may cause drowsiness or fatigue in some users, especially at higher doses.
  • Diarrhea: Some users have reported digestive issues, such as diarrhea or nausea, after using CBD.
  • Changes in mood: While CBD is often used to help regulate mood, some users may experience changes in mood or irritability after using CBD.

Interactions with other medications: CBD may interact with certain medications, including blood thinners and antidepressants, so it is important to speak with a healthcare professional before using CBD if you are taking other medications.

It is important to note that these side effects are not experienced by everyone who uses CBD, and many people tolerate it well. However, anyone considering using CBD for health reasons should be aware of the potential side effects and speak with a healthcare professional before using CBD, especially if they have any pre-existing medical conditions or are taking other medications.

Is using CBD liable to cause moodiness?

Studies On The Effects Of CBD On Mood

There have been several studies examining the effects of CBD on mood, and the results have been mixed. Some studies have suggested that CBD may have anxiolytic effects, meaning that it may help reduce symptoms of anxiety and promote feelings of calm and relaxation.

One study found that CBD reduced anxiety in people with social anxiety disorder. Another study found that CBD may help reduce symptoms of post-traumatic stress disorder (PTSD).

However, other studies have not found significant effects of CBD on mood. For example, a study published in the Journal of Affective Disorders found that CBD did not significantly improve symptoms of depression in people with treatment-resistant depression.

It is important to note that many of these studies have been small and more research is needed to fully understand the effects of CBD on mood. Additionally, factors such as dosage, method of administration, and individual differences may influence the effects of CBD on mood.

The Relationship Between CBD And Anxiety

CBD has been studied extensively for its potential effects on anxiety, and there is some evidence to suggest that it may be helpful in reducing symptoms of anxiety. The endocannabinoid system, which is influenced by CBD, plays a role in regulating mood and anxiety, so it makes sense that CBD may be able to help reduce symptoms of anxiety.

One study published in the Journal of Psychopharmacology found that CBD reduced anxiety in people with social anxiety disorder, and another study published in the Journal of Clinical Psychology found that CBD may help reduce symptoms of post-traumatic stress disorder (PTSD).

In addition to reducing anxiety, CBD may also help reduce symptoms of anxiety-related disorders, such as insomnia and chronic pain. CBD has been shown to have anxiolytic, antipsychotic, and neuroprotective effects, which may help improve overall mental health and well-being.

However, it is important to note that while CBD may be helpful for some people with anxiety, it is not a substitute for medical treatment and should not be used as the sole treatment for anxiety disorders. Anyone considering using CBD for anxiety should speak with a healthcare professional first, as there may be potential interactions with other medications or medical conditions.

The Relationship Between CBD And Depression

While there is limited research on the relationship between CBD and depression, some studies suggest that CBD may have antidepressant effects. The endocannabinoid system, which is influenced by CBD, plays a role in regulating mood, so it makes sense that CBD may be able to help reduce symptoms of depression.

Studies have shown that CBD improved mood and cognitive function in people with a history of depression, and that CBD may have antidepressant effects in animals. CBD may also help reduce symptoms of depression-related disorders, such as anxiety and chronic pain. CBD has been shown to have anxiolytic, antipsychotic, and neuroprotective effects, which may help improve overall mental health and well-being.

However, it is important to note that more research is needed to fully understand the effects of CBD on depression and to determine the optimal dosage and method of administration. CBD should not be used as the sole treatment for depression, and anyone considering using CBD for depression should speak with a healthcare professional first, as there may be potential interactions with other medications or medical conditions.

The Relationship Between CBD And Anger

While there is limited research on the relationship between CBD and anger specifically, some studies suggest that CBD may have a calming effect on the body and mind. CBD interacts with the endocannabinoid system, which plays a role in regulating emotions and mood, so it is possible that CBD may be able to help regulate feelings of anger and promote feelings of calm, although some people have reported irritation as a side effect of using CBD.

One study found that CBD may help reduce symptoms of post-traumatic stress disorder (PTSD), which can include anger and irritability. Another study found that CBD reduced anxiety in people with social anxiety disorder, which can also be associated with anger.

In addition to potentially [reducing] anger, CBD may also help reduce symptoms of anger-related disorders, such as anxiety and depression. CBD has been shown to have anxiolytic, antidepressant, and neuroprotective effects, which may help improve overall mental health and well-being.

However, it is important to note that more research is needed to fully understand the effects of CBD on anger and to determine the optimal dosage and method of administration. CBD should not be used as the sole treatment for anger-related disorders, and anyone considering using CBD for anger should speak with a healthcare professional first, as there may be potential interactions with other medications or medical conditions.

Factors That May Influence The Effects Of CBD On Mood

Several factors may influence the effects of CBD on mood, including dosage, method of administration, individual differences, and the presence of co-occurring conditions.

Dosage is an important factor to consider when using CBD for mood regulation. Studies have shown that different doses of CBD can have different effects on the body and mind, and it is important to find the optimal dosage that works for each individual. It is recommended to start with a low dose and gradually increase the dosage as needed while monitoring any changes in mood.

The method of administration can also affect the effects of CBD on mood. Different methods, such as oral ingestion, sublingual administration, or inhalation, can result in different rates of absorption and onset of effects. Some methods, such as vaping or smoking, may have more immediate effects but may also be associated with greater risks to respiratory health.

Individual differences may also play a role in how CBD affects mood. Factors such as genetics, age, sex, and overall health status can influence how the body responds to CBD. Additionally, co-occurring conditions such as anxiety, depression, or chronic pain may affect the way that CBD interacts with the body and mind.

Overall, it is important to carefully consider these factors when using CBD for mood regulation and to work with a healthcare professional to determine the best course of treatment. While CBD may have potential benefits for mood regulation, more research is needed to fully understand its effects and to determine the optimal dosage and method of administration for each individual.

CBD may have negative enhance some medications ability to damage your liver.

CBD Interactions With Other Medications

CBD may interact with other medications due to its effects on certain enzymes in the liver that are involved in drug metabolism. Specifically, CBD may inhibit the activity of the cytochrome P450 (CYP) enzyme system, which is responsible for metabolizing many medications.

Some medications that may be affected by CBD include:

  • Antidepressants such as fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft)
  • Benzodiazepines such as alprazolam (Xanax) and diazepam (Valium)
  • Beta-blockers such as metoprolol (Lopressor) and propranolol (Inderal)
  • Statins such as atorvastatin (Lipitor) and simvastatin (Zocor)
  • Antipsychotics such as haloperidol (Haldol) and risperidone (Risperdal)
  • Anticonvulsants such as carbamazepine (Tegretol) and phenytoin (Dilantin)

CBD may also interact with blood thinners such as warfarin (Coumadin) and clopidogrel (Plavix), potentially increasing the risk of bleeding. Additionally, CBD may interact with certain medications used for epilepsy, such as clobazam (Onfi), and may increase the risk of side effects.

It is important to note that not all medications will be affected by CBD, and the extent and nature of the interaction may vary depending on factors such as dosage, timing, and individual differences. However, anyone taking medications should speak with a healthcare professional before using CBD to ensure that it is safe and appropriate and to monitor for any potential interactions or side effects.

Other Potential Causes Of Anger Or Irritability

Anger or irritability can be caused by a wide range of factors, including both physical and psychological causes. Identifying the underlying cause is important in order to develop an effective treatment plan and address any potential health concerns.

Physical causes of anger or irritability may include:

  • Sleep disorders: Chronic sleep deprivation can lead to irritability, mood swings, and difficulty regulating emotions.
  • Chronic pain: Long-term pain can be a major source of frustration and may contribute to feelings of anger or irritability.
  • Hormonal changes: Fluctuations in hormones such as estrogen and testosterone can impact mood and lead to feelings of irritability or aggression.
  • Substance use: The use of certain substances such as alcohol or stimulants can lead to irritability or anger, particularly during withdrawal or when use is interrupted.

Psychological causes of anger or irritability may include:

  • Stress: High levels of stress can lead to feelings of irritability and frustration, particularly when stress is chronic or overwhelming.
  • Trauma: Past trauma or ongoing stressors such as abuse or violence can lead to difficulty regulating emotions and may contribute to anger or irritability.
  • Mental health conditions: Conditions such as depression, anxiety, or bipolar disorder may impact mood and contribute to feelings of anger or irritability.

It is important to seek professional help if anger or irritability is impacting daily life or relationships. A healthcare professional can help identify potential causes and develop an appropriate treatment plan, which may include therapy, medication, lifestyle changes, or other interventions as needed.

Safety Concerns Associated With CBD Use

CBD is generally considered safe, with few serious side effects reported in clinical studies. However, there are still some safety concerns associated with CBD use that should be considered before use.

  • Quality control: CBD products are not regulated by the FDA, and many products may contain different amounts of CBD than what is advertised. Some products may also contain contaminants such as pesticides, heavy metals, or solvents, which can be harmful when ingested or inhaled.
  • Drug interactions: CBD may interact with certain medications, potentially increasing the risk of side effects or reducing the effectiveness of the medication. This is particularly important for medications that are metabolized by the liver, such as antipsychotics, antidepressants, and blood thinners.
  • Pregnancy and breastfeeding: There is limited research on the safety of CBD use during pregnancy or while breastfeeding. Some studies have suggested that CBD may have negative effects on fetal development or milk production, and it is generally recommended to avoid CBD use during these periods.
  • Liver toxicity: Some studies have suggested that high doses of CBD may lead to liver damage, particularly in individuals with underlying liver disease or those taking medications metabolized by the liver.
  • THC content: Some CBD products may contain trace amounts of THC, which could potentially cause a positive drug test or lead to intoxication in sensitive individuals.
  • Side effects: While CBD is generally well-tolerated, some individuals may experience side effects such as dry mouth, dizziness, nausea, or changes in appetite or mood.

To minimize potential safety concerns associated with CBD use, it is important to choose high-quality products from reputable manufacturers and to speak with a healthcare professional before starting CBD use, particularly if taking other medications or pregnant/breastfeeding.

Dosage And Administration Of CBD

Determining the appropriate dosage and administration of CBD can be challenging due to the lack of standardized guidelines and individual variations in response. Factors such as weight, age, and medical history may also impact the optimal dosage for an individual.

CBD products are available in a variety of forms, including oils, capsules, gummies, topical creams, and more. Each product may have different recommended dosages and administration methods. It is important to follow the manufacturer’s instructions and speak with a healthcare professional before starting CBD use.

CBD dosages are typically measured in milligrams (mg) and may vary depending on the intended use and method of administration. For example, the dosage of a CBD oil used for anxiety may differ from that used for pain management. A healthcare professional can help determine the appropriate dosage based on individual needs and health concerns.

It is generally recommended to start with a low dosage and gradually increase it until the desired effects are achieved. This approach can help minimize potential side effects and allow for better tolerance of CBD. It is important to note that CBD may take several days or weeks to build up in the body and produce noticeable effects.

The duration of CBD effects may also vary depending on the method of administration. For example, ingesting CBD may take longer to produce effects but may last longer, while inhaling CBD may produce quicker effects but may wear off more quickly. Topical CBD products may produce more localized effects and may not enter the bloodstream in significant amounts.

In summary, determining the appropriate dosage and administration of CBD can be complex and may require the guidance of a healthcare professional. It is important to start with a low dosage and gradually increase until the desired effects are achieved and to follow the manufacturer’s instructions and speak with a healthcare professional before starting CBD use.

Recommendations For Using CBD Safely And Effectively

To use CBD safely and effectively, it is important to follow certain recommendations and guidelines:

  • Choose high-quality products: Look for products that have been tested by third-party labs and have clear labeling with information on CBD content, ingredients, and manufacturing processes.
  • Speak with a healthcare professional: Before starting CBD use, it is important to speak with a healthcare professional, especially if taking other medications, pregnant/breastfeeding, or have underlying health conditions.
  • Start with a low dosage: It is recommended to start with a low dosage and gradually increase until the desired effects are achieved. This approach can help minimize potential side effects and allow for better tolerance of CBD.
  • Monitor for side effects: While CBD is generally well-tolerated, some individuals may experience side effects such as dry mouth, dizziness, nausea, or changes in appetite or mood. It is important to monitor for these side effects and adjust dosage as needed.
  • Avoid THC-containing products: THC can have psychoactive effects and may cause intoxication or positive drug tests. It is important to choose CBD products that are THC-free or have only trace amounts.
  • Store products properly: CBD products should be stored in a cool, dry place away from direct sunlight and heat. It is also important to keep them out of reach of children and pets.
  • Be cautious with topical products: While topical CBD products may have fewer systemic side effects, it is important to avoid applying them to broken or irritated skin or near sensitive areas such as the eyes or mouth.
  • Follow product instructions: Different CBD products may have different dosages and administration methods. It is important to follow the manufacturer’s instructions and speak with a healthcare professional before starting CBD use.
  • Avoid driving or operating heavy machinery: CBD may cause drowsiness or impair coordination in some individuals. It is important to avoid driving or operating heavy machinery until the effects of CBD are fully understood.

In summary, using CBD safely and effectively requires choosing high-quality products, speaking with a healthcare professional, starting with a low dosage, monitoring for side effects, avoiding THC-containing products, storing products properly, being cautious with topical products, following product instructions, and avoiding driving or operating heavy machinery until the effects of CBD are fully understood.

Future Research On CBD And Its Potential Effects On Mood And Emotions.

Despite the growing body of research on CBD and its effects on mood and emotions, there is still much that is not yet fully understood. Further research is needed to better understand the mechanisms by which CBD may influence mood and emotion, as well as the potential benefits and risks of long-term CBD use.

One area of interest is the potential use of CBD for the treatment of psychiatric disorders such as anxiety and depression. While some studies have suggested that CBD may have beneficial effects in these populations, more research is needed to fully understand the potential benefits and risks of CBD for psychiatric disorders.

Additionally, future research may explore the effects of CBD on other emotions and behaviors, such as anger and aggression. As noted earlier, research on the relationship between CBD and anger is limited and conflicting, and further investigation is needed to better understand this relationship.

Another important area of research is the interaction between CBD and other medications. As noted earlier, CBD may interact with certain medications and have potentially harmful effects. Future research can help to better understand these interactions and inform recommendations for safe and effective CBD use in patients taking other medications.

Finally, future research can help to identify individual factors that may influence the effects of CBD on mood and emotions. For example, genetic factors may play a role in how an individual responds to CBD, and further research can help to identify these factors and inform personalized treatment approaches.

In conclusion, while there is much that is still not fully understood about CBD and its effects on mood and emotions, continued research in this area has the potential to lead to new treatments for psychiatric disorders and other emotional and behavioral conditions. By better understanding the potential benefits and risks of CBD use, healthcare professionals can make informed recommendations to their patients and promote safe and effective use of this promising compound.

Don’t worry, be happy
L&C Staff

Authors:
Professor Carlos Bartholomew D’acunto &
Professor Thomas Horatio Cabbage

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